For illustration, in the present study, we determined the triglyceride content in HDL particles and showed that it was not modified after improvement of glycemic control, suggesting that some qualitative abnormalities, such as triglyceride enrichment, which remains present after improvement of glycemic control [17], could be a factor involved in the loss of the inhibitory effect of apoC1 on CETP in T1D. The gene discussed is APOC1; the disease is type 1 diabetes mellitus.