ALB and Abnormal renal physiology: Treatment with EPE in HFD mice not only lowered circulating lipid concentrations, including a reduction in plasma TG, TC, and FFA concentrations but also reduced BUN and plasma creatinine levels in both urine and blood while also lowering urine albumin levels in HFD-induced diabetic mice, implying that EPE displayed antihyperlipidemic activity in HFD-fed mice, and EPE possesses protective activity on renal dysfunction.