The results showed that all differentially expressed genes in T2D samples were significantly enriched in the following processes: NF-κB targets, focal adhesion and the PI3K–AKT–mTOR signaling pathway, integrated TGF-β EMT up, hypoxia up, and other biologically related functions and signaling pathways. The gene discussed is NFKB1; the disease is type 2 diabetes mellitus.