These pathways include genes targeted by miRNAs in adipocytes, rho GTPases activating rho-tekins and rho-philins, zamora Nos2 targets, Chiba response to TSA, SARS-CoV infections, P2Y receptors, Nikolsky breast cancer 20q11 amplicon, uptake and actions of bacterial toxins, autophagy, and purinergic signaling. This evidence concerns the gene NOS2 and severe acute respiratory syndrome.