AKT1 and type 2 diabetes mellitus: The findings indicated that all genes in T2D samples were significantly enriched in biologically related functions and signaling pathways, such as NF-κB targets (Figure 5D), focal adhesion and the PI3K–AKT–mTOR signaling pathway (Figure 5E), integrated TGF-β EMT up (Figure 5F), and hypoxia up (Figure 5G).