and Phaeodactylum tricornutum significantly reduced the proliferation of the liver cancer cell line HepG2 by inducing cell apoptosis without affecting the cell cycle and mitosis of tumor cells, and it showed immune-modulatory activity by stimulating macrophage cytokine production (such as IL-6, IL-10, and TNF-α) [58,59]. The gene discussed is TNF; the disease is neoplasm.