Meanwhile, the cis-target gene KRTAP15-1 of the lncRNA MSTRG.9225.1 was significantly enriched during keratinization and epidermal cell differentiation as well as epithelium and skin development; the trans-target gene KRT10 was significantly enriched in keratin differentiation, and the above GO terms were closely related to the growth and development of HF and fiber characteristics [4,35]. This evidence concerns the gene KRTAP1-5 and hydrops fetalis.