We also investigated the regulatory effects of dhAvD on CCL20 and IL-23, keratinocyte-derived factors that enhance Th2 cytokines that are highly expressed in atopic dermatitis [6,27,28,29], and their downstream molecules, MMP-9 and MMP-12 [30,31] (Supplementary Figure S1). The gene discussed is CCL20; the disease is atopic eczema.