NFKB1 and rheumatoid arthritis: Under RA conditions, all three subpopulations upregulated CXCL1, CXCL2, CXCL3, CCL4, CCL4L2, IL-1β, TNFAIP3, ICAM1, PLAU and TNF in the NF-κB signalling pathway to varying extents [45].