In contrast, in our study we focused on the most aggressive types of breast cancer, which are the TNBC and HER-2-enriched types [41], and therefore MDA-MB-231 and SK-BR-3 cells were used for a functional in vitro model This in vitro model facilitated a more profound investigation into the role of RBMS 3 in IDC subtypes. Here, ERBB2 is linked to breast cancer.