A study of Niu and colleagues [129] showed overexpression of the lncRNA XLOC_003810 in thymic CD4+ T cells from MG thymomas compared to controls cells and provided a demonstration that the lncRNA overexpression enhanced the transdifferentiation of Tregs toward Th17 cells, whereas its silencing attenuated the Th17/Tregs imbalance. The gene discussed is CD4; the disease is thymoma.