CD274 and breast cancer: Domvri K et al. designed specialized copper sulfide nanocarriers (CuSNC) encapsulated with Epacadostat/Dasatinib (EPDA) complexes to nano-target Tregs in a mouse model of triple-negative BC 4T1 tumors and found that CuS/EPDA inhibited metastatic BC tumor growth in combination with anti-PD-L1 drugs [264].