They reported that iPSC-CMs derived from dermal fibroblasts of patient with inherited CPVT1 (caused by mutation in the RYR2 p.F2483I), exhibited arrhythmias and delayed afterdepolarizations (DADs) after catecholaminergic stimulation. This evidence concerns the gene RYR2 and catecholaminergic polymorphic ventricular tachycardia 1.