They documented in their findings that “treating preeclampsia like rat models with the protein PD-L1-Fc leads to a reverse of the Treg/Th17 imbalance and thereby to a protective effect on mother and fetus.” Few other studies have also substantiated this novel role of PD-1/PD-L1 pathway [39,40]. The gene discussed is PDCD1; the disease is preeclampsia.