SPDL1 and preeclampsia: A positive correlation was observed between IL-6, hsCRP, and sPD-L1 (Table 2), which may be explained as an attempt to stimulate the expression of PD-1/PD-L1 by the ongoing inflammation present in preeclampsia due to immunological dysregulation and imbalance between PD-1/PD-L1 and Tregs/Th17 ratio [59,60,61].