Asthma, aspirin intolerance, and cytokine expression (IgE, specific IgE to Staphylococcus aureus enterotoxin, eosinophilic cationic protein (ECP), and IL-5): Van Zele et al. studied the cytokine profile in CRSwNPs that underwent FESS for the first time and recurrent CRSwNPs [15]. The gene discussed is IGHE; the disease is asthma.