TNC and apparent mineralocorticoid excess: Conditions such as myocarditis, pericarditis, heart failure, and coronary artery atherosclerosis can also lead to elevated Tn levels, which may reduce the reliability of Tn as a single diagnostic indicator. Given these advantages and limitations, clinicians encountering patients suspected of APE need to make comprehensive judgments by combining the patient's clinical symptoms, medical history, and other laboratory test results.