NFKB1 and colitis: In the previous studies, it have reported improvements in memory through brain inflammation and antidiabetic effects, improvement in intestinal inflammation in dextran sulfate sodium (DSS)-induced colitis, reduction in fatty liver and body weight in a high-fat diet model, and water extract from CGJ (fermented by Bacillus amyloliquefaciens, SRCM100730) and polysaccharides from CGJ increased immune enhancement and immune regulation through activation of the NF-κB pathway in RAW 264.7 macrophages and cyclophosphamide (CP)-induced immunosuppression [[26], [27], [28], [29], [30]].