In a multivariate linear regression model we analyzed the influence of age, sex, BMI, CHF severity, baseline values of NT-proBNP, KCCQ overall score, exercise capacity (Wmax), exercise-related PA (MET*h/week) by questionnaire (Freiburger PA Questionnaire), and the presence of atrial fibrillation and coronary artery disease on the change of exercise-related PA by questionnaire (V12 minus V0). The gene discussed is NPPB; the disease is atrial fibrillation.