In a previous study, CXB and 2,5-dimethylcelecoxib (DMC), an analogue of CXB with no apparent effect on COX-2 [11], was combined with two canonical chemotherapy drugs, paclitaxel (PA) or cisplatin (CP), to deter growth of human cervical HeLa, human cervix cancer SiHa and human glioblastoma U373 cancer cells in monolayer and HeLa multicellular tumor spheroids [12]. The gene discussed is PTGS2; the disease is cancer.