PMVK catalyzes the cation‐dependent reaction between Mevalonic‐5‐phosphate and ATP to form mevalonate‐5‐diphosphate and ADP and represents a key step in the mevalonate pathway for isoprenoid/sterol biosynthesis and protein prenylation.[10] Although the mevalonate pathway has been implicated in various aspects of cancer development and progression,[10, 11] the role(s) of PMVK in the establishment of tumor immunity by altering tumor metabolism remains unknown. The gene discussed is PMVK; the disease is cancer.