In addition, we observed no changes in CD80 or CD86 staining and no changes in the phagocytosis of tumor-infiltrating DCs in tumors (detected by the expression of zsGreen), ruling out the effects of IR or Ythdf1 deletion on the costimulatory molecules or phagocytic activity in Ythdf1-cKO mice following IR (Supplemental Figure 4, C–E). The gene discussed is CD86; the disease is neoplasm.