The development of 99mTc-PentixaTec provides an effective means, [99mTc]-N4-dap-r-a-Abz-CPCR4 ([99mTc]-N4-L6-CPCR4, 99mTc-PentixaTec), for CXCR4 imaging, and the first human study was performed in five patients with hematological malignancies by Konrad et al. [18]. This evidence concerns the gene CXCR4 and hematologic disorder.