We looked at this on a case-by-case basis and found that the CD20+CD27+CD24+CD40+CXCR4+CXCR5+ B cells in MC14 of 1 of the 10 total HIV+ pre-NHL (cART-naïve) samples were specifically positive for Ig kappa LC and negative for Ig lambda LC (median expression value of Ig kappa LC = 3.40 vs. median expression value of Ig lambda LC = 0.24). Here, CXCR4 is linked to non-Hodgkin lymphoma.