For in-depth and high-dimensional analysis, we performed unsupervised clustering of CD19+ B cells from concatenated FCS data files for each group after mass cytometry: 10 HIV-negative (12 data files), 20 HIV+ cART-naïve samples (22 data files), and 10 HIV+ pre-NHL (cART-naïve) samples (11 data files). This evidence concerns the gene CD19 and non-Hodgkin lymphoma.