Factors associated with worse PFS were otherwise identical with those associated with worse OS, and included high grade B cell lymphoma with Myc/Bcl2 translocations (p<0.03), higher IPI (p<0.001), more lines of therapy received (p<0.001), and not experiencing CR (p<0.001, median OS of 15 months). The gene discussed is MYC; the disease is B-cell non-Hodgkin lymphoma.