Moreover, the lncRNA colorectal neoplasia differentially expressed has been implicated in impairing apoptotic activity and promoting resistance to osimertinib and afatinib via the eIF4A/MUC1/EGFR pathway in (osimertinib and afatinib-resistant) EGFR-mutated lung cancer cells (50). This evidence concerns the gene EGFR and lung carcinoma.