CD28 and benign prostatic hyperplasia: This study revealed an inverse correlation between CD28- CD25++ CD8br AC (OR = 0.9603, 95% CI = 0.9239 ~ 0.9981, p = 0.0399) and CD127- CD8br %T cell (OR = 0.8837, 95% CI = 0.8154 ~ 0.9576, p = 0.0025) and a decreased risk of BPH.