GDI2 and colorectal carcinoma: In CRC cells, the GDI2 mRNA expression level and protein expression level of cells in the sh-GDI2#2 group were lower than those in sh-GDI2#1 and sh-GDI2#3 groups, and significantly lower than those in the sh-NC group (P < 0.01) (Fig. 2B–D).