In the results of the wound healing assay (Fig. 5I), the healing distance of CRC cells in the sh-GDI2+pcDNA-RAB5A group was significantly increased compared with the sh-GDI2 group (P < 0.05, P < 0.01) at 4 h and 24 h. The gene discussed is GDI2; the disease is colorectal carcinoma.