Among NUP98 target genes, loss of CDK6 has a significant impact on NUP98 fusion‐driven leukemogenesis, a feature shared with other AML subtypes such as KMT2A‐rearranged or RUNX1::RUNX1T1‐positive AMLs.135, 169, 170. The gene discussed is NUP98; the disease is acute myeloid leukemia.