One-third of patients show a strong family history, with most common genetic causes of FTD being autosomal dominant pathogenic variants in the progranulin (GRN) gene,1,2 the microtubule-associated protein tau (MAPT) gene,3 and the chromosome 9 open reading frame 72 (C9orf72) gene.4 The gene discussed is MAPT; the disease is frontotemporal dementia.