Using an initial in-silico approach, different genes encoding enzymes involved in the protein glycosylation pathways, was suggested to be up (e.g. Neuraminidase 1—Neu1, and α-1,3-mannosyltransferase—ALG3, or down (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 –ST8Sia2, and α-Glucosidase 2—GANAB) regulated in the course of infection in human cardiomyocytes (S1 Fig). The gene discussed is NEU1; the disease is infection.