(G–H) ChIP-qPCR showing enrichment of HNF4α (G) and p-S133-CREB1 (H) at Ctnnb1 promoter in native colon tissues of WT (n= 3) mice, tumor tissues of ApcMin/+ (n= 3) mice, and Ctnnb1Δi.enh;ApcMin/+ (n= 3) mice. Here, CREB1 is linked to neoplasm.