TNF and metabolic syndrome: As a limitation, it is essential to consider the possible influence ofunmeasured variables, such as genetically derived dyslipidemia, biomarkers (likeC-reactive protein, apolipoproteins B and AI, fibrinogen, TNF, and IL-6), levels ofphysical activity, and duration of sedentary time, given that cardiometabolic riskis influenced by a multitude of factors.