Furthermore, some patients are at high risk of relapse/refractory (R/R) disease following first‐line R‐CHOP due to higher International Prognostic Index (IPI) score4 or high‐grade lymphoma classification (MYC plus BCL2 and/or BCL6 rearrangements, also known as double or triple hit lymphomas).5 The gene discussed is MYC; the disease is lymphoma.