Poor evidence for shared causal variants was found for MCSF with risk of hospitalization due to COVID-19, CTACK with risk of COPD, IL-1ra with FVC, PDGFbb with FEV1, and sICAM with FEV1/FVC, which might indicate genetic confounding in those associations or be a result of limited power (weak signals) (Tables S5 and S6). The gene discussed is CCL27; the disease is COVID-19.