The symptoms range from most commonly reported fever, pleuritic chest pain, and pleural and pericardial effusion to uncommon features, such as pulmonary infiltrate, massive pleural effusion, and even fatal cardiac tamponade [8]. A proposed criterion requires at least two of the following to be present to diagnose PCIS following cardiac injury: (1) fever without an alternative cause, (2) pleuritic chest pain, (3) pleural or pericardial rub, (4) Pleural or pericardial effusion, and (5) elevated CRP [10]. The gene discussed is CRP; the disease is cardiac tamponade.