Pre-clinical studies investigating the impact of GLP-1 RAs specifically on breast cancer progression have produced conflicting results, which vary based on the receptor status of the cancer cell lines studied (Ligumsky et al., 2012; Alanteet et al., 2024; Alanteet et al., 2021; Zhao et al., 2018; Shadboorestan et al., 2021; Liu et al., 2022). This evidence concerns the gene GLP1R and breast cancer.