Shen et al. developed pH-sensitive nanoparticles for the combined delivery of BLZ-945 and platinum to consume TAMs and kill tumor cells, achieving a combination of chemotherapy and immunotherapy.343,344 Studies have demonstrated the effectiveness of CSF-1R inhibitor-loaded nanoparticles in consuming TAMs and inhibiting tumor growth and metastasis.344 Surface markers on macrophages, like CD206, can likewise serve as therapeutic targets. Here, CSF1R is linked to neoplasm.