By targeting ADCP induced by the CD47-SIRPα axis, mouse macrophages in tumor models can be biased toward the M1-like phenotype, promoting the anti-tumor immune response.347,348 Zhang et al. developed nanogels assembled with anti-signal transducer and activator of transcription 3 (anti-STAT3) siRNA. This evidence concerns the gene STAT3 and neoplasm.