Of 326 pediatric patients with COVID-19 confirmed by a positive nasal swab SARS-CoV-2 by RT-PCR, 79.8% (260/326, 95% CI: 75.0%-84.0%), 68% (145/212, 95% CI: 61.7%-74.6%), 93.4% (284/304, 95% CI: 90.0%-96.0%), and 86.4% (204/236, 95% CI: 81.4%-90.5%) were positive for N total antibodies, S IgM, S IgG, and N IgG, respectively (Fig 1). This evidence concerns the gene CD40LG and COVID-19.