NPY and Dravet syndrome: Interestingly, various neurotransmitter and receptor systems have been found altered in DS models, including the glutamatergic (Belichenko and others 2007; Gurjinder Kaur and others 2014), GABAergic (Best and others 2012), and neuropeptide Y systems (Duchon and others 2021), although most of these dysregulations have been found in mouse models and still need to be replicated in humans with DS (Duchon and others 2021).