Sex, primary tumor site, functional symptoms, SSA type, ECOG at treatment start, and chromogranin A elevation were not prognostic for PFS, but there was a trend for high Ki-67 (> 10%) and SSA treatment line (first versus later line) to be prognostically relevant (p = 0.077 and p = 0.065, respectively), see Table 2. This evidence concerns the gene MKI67 and neoplasm.