MFN2 and amyotrophic lateral sclerosis: The first report of a patient with co-occurrence of Charcot–Marie–Tooth disease type 2A and amyotrophic lateral sclerosis associated with an MFN2 mutation dates back to 2011.8 A second report was published in 2023 by Vinciguerra et al.,9 detailing one amyotrophic lateral sclerosis/frontotemporal dementia patient with the p.(Asp194Ala) mutation that is now included in our study (Patient 4).