Further, the ROC curve analysis confirmed the reliability of MAPK8IP3 expression as a molecular marker in differentiating RA from OA in bone marrow samples (AUC, 0.85; 95% CI, 0.66-1; p=0.015) with a sensitivity of 100% and a specificity of 75% (cutoff <4.95) (Fig. 3B). The gene discussed is MAPK8IP3; the disease is rheumatoid arthritis.