Invasion and metastasis:  CRC cells infected with Fusobacterium nucleatum  showcase heightened invasiveness into their surrounding   environment. These infected cells attract myeloid cells to   the bacterial niches, accelerating migration rates   significantly. This process is mediated through various   signaling pathways crucial for cancer metastasis, including   extracellular matrix remodeling and modulation of cell   adhesion and migration via ERK1 and ERK2. This evidence concerns the gene MAPK1 and colorectal carcinoma.