Interestingly, in the research, they also showed that the cytokine IFN-γ played a pivotal role in Th-1-mediated autoimmune disorders by directing the immune response towards a Th1 phenotype through promoting T cell differentiation and inhibiting the development of Th2 cells, as observed in autoimmune disorders like GBS (35). This evidence concerns the gene NELFCD and Guillain-Barre syndrome.