PLAG1 and gastric cancer: Chen et al. (2023) found that exosomal circ0091741 derived from gastric cancer cells regulates miR-330-3p/TRIM14/Dvl2/Wnt/β-catenin axis to induce autophagy and Oxaliplatin resistance in gastric cancer cells. The expression of PLAG1 and ATG12 was activated by CircPOFUT1-regulated miR-488-3p, which improved the malignant phenotype and autophagy-related chemical resistance in gastric cancer cells (Luo et al., 2023).