An aged patient is more susceptible to hyponatremia due to a number of factors, including decreased glomerular filtration rate, diminished kidney function, increased production of antidiuretic hormone (ADH) in response to a particular osmotic stimulation, numerous medications they take, and coexisting disorders. The current study provides important insights into the clinical characteristics, underlying causes, and volume status of elderly patients with hyponatremia. This evidence concerns the gene AVP and Hyponatremia.