As a result of significantly low levels of alpha-galactosidase, globotriaosylceramide, and globotriaosylsphingosine enzymes which had been ordered by the clinical team, a concern for Fabry disease was raised, a genetic test was requested, and right heart catheterization with endomyocardial biopsy (EMB) was performed. This evidence concerns the gene GLA and Fabry disease.