DNM3OS and microcephaly: Patients with small deletions of this chromosomal region, affecting DNM3OS and the incumbent miRNAs, have skeletal abnormalities including short stature, microcephaly and brachydactyly (Lefroy et al., 2018), and, in mouse, are somewhat phenocopied by deletion of Dnm3os and, therefore, the miR199a∼214 cluster (Watanabe et al., 2008).