TheT. crassiceps-derived peptide glycerol kinase-1 was found to treat cancer by promoting CD8+ T cell responses in a murine model of melanoma, mediated by suppressing the expression of PD-1 on tumor-infiltrating CD8+ T cells and by reducing the high expression levels of tumor-induced PD-1 ligand 1 on the surface of DCs[134]. Here, CD8A is linked to melanoma.