To further understand the protective effect of anti-Ov-TSP-2 antibody against opisthorchiasis, Phumrattanaprapinet al[89] transferred two anti-Ov-TSP-2 monoclonal antibodies, 1D6 and 3F5, to hamsters at one day before parasite infection, and found that 1D6 and 3F5 might block the uptake of fluke EVs by BECs through combining with host BECs. The gene discussed is THBS2; the disease is opisthorchiasis.