In lung cancer patients, the relative expression of lncRNA GIAT4RA and lncRNA AATBC was significantly upregulated (P = 0.024, 0.001, respectively), while lncRNA Sirt1-AS was significantly downregulated (P = 0.004), and SMARCB1 showed insignificant differences (P = 1.000) compared to the control group. The gene discussed is GPAT4-AS1; the disease is lung carcinoma.