To study the pathophysiology of lung fibrosis, we measured the two fibrosis markers associated with IPF such as collagen [46–48], and α-SMA, although the latter has been currently debated as a sole marker for studying fibrosis [49] as its expression doesn ́t mean that a cell produces high amounts of collagen [50]. This evidence concerns the gene ACTA1 and idiopathic pulmonary fibrosis.