We aimed to evaluate the relationship of A. lumbricoides infection with several Bregs subsets previously reported in relation with other helminth infections [10,24]: IL-10+ CD1dhi, IL-10+CD5+, CD5+CD1dhi and IL-10+CD24hiCD38hi B cells as well as the CD25+CD71+CD73- B cell phenotype, first reported by our group to be associated with IL-10 production and inhibition of T cell proliferation [23]. This evidence concerns the gene NT5E and helminthiasis.